- This article is about the spider. For the cat, see Guido (cat). For the mysterious creature, see Guido (creature).
Guido is a house spider. Garfield hired Guido to kill a fly in 1998, he later ate him. Guido once gave Garfield a Christmas hat, but it was spider-sized. Guido would also swat Garfield for two flies (although he wound up only getting one).