The squirrels from The Garfield Show are the residents of a tree in the backyard of the Arbuckle house. They were initially known to torment Odie (with Garfield watching it, as it was one of his favorite activities). However, after Odie befriends one of the squirrels (named Devil), the squirrels decide that they can get along with dogs (having previously thought they couldn't, hence why they previously antagonized Odie). This, however, ends up "cancelling" one of Garfield's favorite shows.
They later dealt with a mole who tunneled underneath the backyard; they helped Garfield in diverting the mole to a new location.